Financial Results for 3Q of FYE 3/2018
1. Financial Results for 3Q of FYE 3/2018
Basic Financial Data (Consolidated)
Consolidated Statement of Income
Non-operating Profit and Loss/Extraordinary Profit
and Loss
Sales Revenue and Operating Profit by Business
Quarterly Operating Profit
Consolidated Balance Sheet
Consolidated Cash Flows, Capital Expenditures,
FYE 3/2018
9M
(Apr
-
Dec)
FYE 3/2017
9M
(Apr
-
Dec)
YoY
Actual
Actual
Increase/ Decrease Percentage Increase/ DecreaseSales Revenue
25,034
21,887
3,147
14.4
Operating Profit
2,286
3,459
-1,173
-33.9
Ordinary Profit
2,119
3,391
-1,271
-37.5
Quarterly Profit Attributable to
Owners of Parent
1,441
2,354
-913
-38.8
Dec.31,2017
FYE 3/2017
End of year
Increase/
Decrease
Total Assets
49,399
52,081
-2,682
Equity Capital
31,312
28,078
3,234
Interest-bearing
Liabilities
9,646
13,967
-4,320
(In millions of yen)
(In millions of yen)
FYE 3/2018
9M
(Apr
-
Dec)
FYE 3/2017
9M
(Apr
-
Dec)
YoY
Increase/ Decrease Percentage Increase/ Decrease
Sales Revenue
25,034
21,887
3,147
14.4
Gross Profit
5,336
6,160
-823
-13.4
Gross Profit Margin (%)
21.3
28.1
-
-
SG&A
3,050
2,700
350
13.0
Operating Profit
2,286
3,459
-1,173
-33.9
Operating Profit Margin (%)
9.1
15.8
-
-
Ordinary Profit
2,119
3,391
-1,271
-37.5
Profit before Income Taxes
1,935
3,295
-1,359
-41.3
Quarterly Profit Attributable
to Owners of Parent
1,441
2,354
-913
-38.8
■
Non-operating Profit and Loss
■
Extraordinary Profit and Loss
<Non-operating Profit and Loss/Extraordinary Profit and Loss>
(In millions of yen)
FYE 3/2018
9M
(Apr
-
Dec)
FYE 3/2017
9M
(Apr
-
Dec)
Non-operating Profit
236
440
Interest income
6
8
Dividend income
2
2
Share of profit of entities accounted for using
equity method
-
22
Gain on valuation of
derivatives
159
310
Other
68
97
Non-operating Expenses
403
509
Interest expenses
32
38
Share of loss of entities accounted for using equity
method
67
-
Foreign exchange losses
166
351
Other
136
119
(In millions of yen)
FYE 3/2018
9M
(Apr
-
Dec)
FYE 3/2017
9M
(Apr
-
Dec)
Extraordinary Profit
18
28
Gain on sales of
non-current assets
18
28
Extraordinary Losses
203
123
Loss on abandonment
of non-current assets
203
46
Loss on sales of
non-current assets
0
0
Impairment loss
-
76
Loss on sales of
(In millions of yen) (In millions of
yen)
<Sales Revenue and Operating Profit by Business>
FYE 3/2018
9M
(Apr
-
Dec)
FYE 3/2017
9M
(Apr
-
Dec)
Percentage Increase/
Decrease
Sales Revenue Operating Profit Sales Revenue Operating Profit Sales Revenue Operating ProfitHigh-purity Chemical Business
21,693
2,347
18,648
3,460
16.3
-32.2
[Hig h -p u ri ty Ch e m ica l B u sin e ss: B re a kd o w n
] Surface Treatment 1,409 1,490 -5.4
Alternatives for CFCs 1,855 1,665 11.4
Batteries 4,081 3,847 6.1
Semiconductors/LCDs 11,375 8,952 27.1
Semiconductor Devices 517 349 48.1
Catalysts 716 649 10.2
Gypsum 62 56 11.9
General products 977 1,035 -5.6
Other 697 601 16.0
Transportation Business
3,194
604
3,088
553
3.4
9.2
Medical Business
-
-704
-
-585
-
-
Other Business
146
26
150
20
-2.6
31.7
1Q
2Q
3Q
4Q
1Q
2Q
3Q
4Q
1Q
2Q
3Q
4Q
Sales Revenue
6,745
7,057
6,789
6,918
7,187
6,757
7,941
7,963
8,159
8,561
8,314
Operating Profit
86
288
404
609
960
1,025
1,473
912
888
936
461
Operating Prof it Margin
1.3%
4.1%
6.0%
8.8%
13.4%
15.2%
18.6%
11.5%
10.9%
10.9%
5.5%
FYE 3/2016
FYE 3/2017
FYE 3/2018
86
288
404
609
960
1,025
1,473
912
888
936
461
0
200
400
600
800
1,000
1,200
1,400
1,600
(In millions of yen)
(In millions of yen)
Dec.31,2017
FYE 3/2017
End of Year
Increase/
Decrease
(In millions of yen)
Current Assets
25,985
28,069
-2,084
Cash and Deposits
9,663
14,361
-4,698
Notes and Accounts Receivable - trade
9,251
7,867
1,383
Non-current Assets
23,413
24,011
-597
Property, Plant and Equipment
21,485
22,072
-587
Intangible Assets
139
129
10
Investments and Other Assets
1,788
1,808
-20
Current liabilities
9,979
12,566
-2,586
Short-term Loans Payable
1,950
2,320
-370
Long-term Loans Payable
within 1 year
3,009
3,684
-674
Non-current liabilities
6,794
9,998
-3,203
Bonds Payable
-
2,000
-2,000
Long-term Loans Payable
4,686
5,962
-1,275
Net Assets
32,624
29,516
3,107
Shareholders' Equity
30,934
27,771
3,163
Liabilities and Net Assets
49,399
52,081
-2,682
(In millions of yen)
FYE 3/2018
9M
(Apr
-
Dec)
FYE 3/2017
9M
(Apr
-
Dec)
Capital Expenditures
1,987
1,355
Depreciation & Amortization
2,502
2,340
Research & Development Expenses
1,088
960
2. Financial Forecast for FYE 3/2018
Financial Forecast
<Financial Forecast>
(In millions of yen)
FYE 3/2018
Revised Full-year
forecast
( Feb.9, 2018 )
FYE 3/2018
Revised Full-year
forecast
( Aug.8, 2017 )
FYE 3/2017
Full-year results
FYE 3/2016
Full-year results
Sales Revenue
33,400
33,300
29,850
27,509
Operating Profit
2,100
4,700
4,372
1,388
Ordinary Profit
1,900
4,700
4,154
1,044
Net Profit Attributable to
Owners of Parent
1,400
3,300
2,824
1,323
Current Net Profit Per
Share
110.38
268.20
234.56
110.33
Capital Expenditures
3,000
3,010
2,328
1,302
Depreciation &
Amortization
3,350
3,309
3,117
3,525
Research & Development
FYE 3/2018 Revised Full-year Forecast ( Feb.9, 2018 )
FYE 3/2018 Revised Full-year Forecast ( Aug.8, 2017 )
FYE 3/2017 Full-year results FYE 3/2016 Full-year results Sales Revenue Operating Profit Sales Revenue Operating Profit Sales Revenue Operating Profit Sales Revenue Operating Profit High-purity Chemical
Business
28,960
2,320
29,100
5,030
25,501
4,422
23,087
1,390
[Hig h -p u ri ty Che m ical B u sine ss: B rea kd o w n
] Surface Treatment 1,840 1,720 2,033 2,097
Alternatives for CFCs 2,360 3,410 2,463 2,023
Batteries 5,270 5,670 5,072 2,989
Semiconductors/LCDs 15,670 14,350 12,310 12,224
Semiconductor
Devices 710 760 527 545
Catalysts 910 770 854 846
Gypsum 70 110 94 107
General products 1,270 1,450 1,342 1,461
Other 860 860 803 791
Transportation Business
4,250
770
4,020
720
4,143
698
4,195
664
Medical Business
-
-1,010
-
-1,080
-
-792
-
-691
Other Business
190
30
180
30
204
30
226
6
(In millions of yen)
3. STELLA CHEMIFA CORPORATION
Corporate Profile/Sales Office Locations/Plant
Locations
(as of December 31, 2017)
List of Affiliated Companies
Corporate profile
Corporate name:
STELLA CHEMIFA CORPORATION
Head Office:
Midosuji MTR Building 3F, 3-6-3 Awaji-machi, Chuo-ku, Osaka
Founded:
February 1916
Established:
February 1944
Capital:
4,829,782,512 yen
Representatives:
Chairperson, Representative Director: Junko Fukada
President, Representative Director: Aki Hashimoto
URL
http://www.stella-chemifa.co.jp/
Sales office
Osaka Sales Department: Midosuji MTR Building 4F, 3-6-3 Awaji-machi,
Chuo-ku, Osaka
Tokyo Sales Department:
Tokyo Tatemono Yaesu Building 2F, 1-4-16 Yaesu,
Chuo-ku, Tokyo
Factory addresses
Sanpo Factory:
7-227 Kaisan-cho, Sakai-ku, Sakai
Izumi Factory:
1-41 Rinkai-cho, Izumiotsu
Kitakyushu Factory: 1-1 Kurosakishiroishi, Yahatanishi-ku, Kitakyushu
Base
Logo
Corporate Name
Business Segment
Head Office:
At
ho
me
Stella Chemifa Corporation High-purity Chemical
Business Chuo-ku, Osaka
Blue Express, Inc. Transportation Business Sakai-ku, Sakai
Blue Auto Trust Co., Ltd. Other Business Sakai-ku, Sakai
Stella Pharma Corporation Medical Business Chuo-ku, Osaka
Ab
roa
d
Stella Chemifa Singapore Pte Ltd.
High-purity Chemical
Business Singapore
Stella Express (Singapore) Pte Ltd. Transportation Business Singapore
Blue Express (Shanghai) International Trade Inc.
High-purity Chemical
Business China
Blue Express (Shanghai) International
Freight Forwarding Co., Ltd. Transportation Business China
Zhejiang Blue Star Chemical Co., Ltd. High-purity Chemical
Business China
FECT Co., Ltd. High-purity Chemical
Business South Korea
Quzhou BDX New Chemical Materials Co., Ltd.
High-purity Chemical
Our products, fluorine compounds, have continued to be used in the manufacturing process of various products.
Segment name
Main product
Applications
Surface treatment
Hydrofluoric acid for industrial use
Used for acid cleaning of stainless steel and for thinning glass
substrates for LCDs
Alternatives for CFCs
Anhydrous hydrofluoric acid
Material for chlorofluorocarbon and fluorine resin
Batteries
Lithium hexafluorophosphate
Electrolyte for electrolytic solution of lithium-ion secondary
batteries
Semiconductors and
LCDs
High-purity hydrofluoric acid
Cleaning solution for silicon wafers and LCDs
Solar batteries
High-purity buffered hydrofluoric
acid
Semiconductor
devices
High-purity fluoride
(CaF
2, PbF
2, MgF
2, AlF
3, and
others)
Lens material for i-line steppers and cameras
Potassium fluoride
Auxiliary agent for manufacturing tantalum for tantalum
capacitors
General products
Tin fluoride
Quasi-drug
Semiconductors and LCDs
Features of our products
Results and forecast of world semiconductor
market scale by regions
New business development in growing market
Maintenance and strengthening of quality edge
Change in shipping volume of high-purity
<Features of our products>
(1) With our ultra purification technology and ultra sensitive technology, we are able to supply the ultra-high-purity
hydrofluoric acid and the ultra-high-purity buffered hydrofluoric acid with the best quality in the world.
(2) Product Lineups are readied to respond the customer requirements, including suppression of adhering particles,
suppression of increased roughness of wafer surfaces, and others, for the semiconductor and FPD manufacturing
process.
Description
The ultra-high-purity chemicals used for wet etching and wet cleaning of silicon wafers in
manufacturing semiconductors, FPDs, solar batteries, and MEMS.
The ultra-high-purity chemical mixed hydrofluoric acid and ammonium fluoride.
BHF
(buffered hydrofluoric acid)
The chemical mixed 50% hydrofluoric acid and 40% ammonium fluoride solutions.
LL BHF
BHF with various functionalities by adding a surfactant
LAL BHF
BHF containing a surfactant which has achieved extended service life and other advantages by
optimizing the concentration of ammonium fluoride.
LA BHF
BHF which etches silicon oxide at high speed.
Silicon oxide etchant with High Selectivity for silicon nitride.
Silicon oxide etchant without damaging to silicon and poly-silicon absolutely.
Product name
(Semiconductor and LCDs)
Ultra-high-purity hydrofluoric acid
Ultra-high-purity buffered
hydrofluoric acid
HSN Series
<Results and forecast of world semiconductor market scale by regions>
Source: World Semiconductor Trade Statistics Inc. (WSTS)
69,324
68,738
65,537
73,561
75,334
75,471
37,459
34,258
32,707
35,543
36,669
37,110
34,830
31,102
32,292
34,408
35,069
35,219
194,230
201,070
208,395
234,288
240,884
239,358
0
50,000
100,000
150,000
200,000
250,000
300,000
350,000
400,000
2014
2015
2016
2017
2018
FY 2019
($ million)
USA
Europe
Japan
Asia-Pacific
Results
Forecast
2014
2015
2016
2017
2018
2019
<New business developments in growing markets>
Large investments in semiconductor factories are in the pipeline for China and other parts of East Asia by 2019.
While the Chinese semiconductor market is currently small, the industry in Taiwan and China is expected to grow increasingly.
*We will move ahead by implementing effective sales strategies in the Chinese market.
ー カ ー 建 設 地 点 名 生 産 品 目 サ イ 生 産 能 力 計 画
N-Y2
3D-NAND
インチ
1
万枚/月
年度 け イン導入Y6
3D-NAND
インチ
年度夏完成イ ン テ
大 連
Fab2
3D-NAND
インチ
万枚/月
建設中。 年 月 装置導入ロ ー
フ ァ
ン
ー
成 都
Fab 11
ファン
ー
インチ
万枚/月
建設中。 年 稼働マ イ
ロ ン テ
ロ
ー
広 島
Fab 15
DRAM
インチ
万枚/月
の量産 向けて 新棟建設中。サ
ン 電 子
西 安
イン Ⅱ3D-NAND
インチ
万枚/月
万枚/月 ら 年 万枚/月 張TSMC
南 京
ファン
ー
インチ
万枚/月
年後半 ら生産開始福 建 省 電 子 信 息 ;
※
技 術 供 与泉 州
ニッチ
A
インチ
万枚/月
年 月建屋竣工。 年 稼働。Nexchip
ワ ー チ ッ プ )
合 肥
液晶
イ
ー
IC
インチ
万枚/月
年 ~ 月 . 万枚/月の装置挿入。
年 万枚/月追加。
ホ ワ
ー ;
上 海
Fab 2ファン
ー
インチ
万枚/月
年 装置導入。イ
ロ ン
ー
合 肥
DRAM
インチ
.
万枚/月
年 月 装置搬入。長 江 存 儲 科 技 ;
※ 紫 光 集 団 資 参 加
武 漢
3D-NAND
インチ
万枚/月
年 装置導入。 年 万枚/月
構想も。
東 芝
四 日 市
Manufacturer
Toshiba Memory
Place of
construction Base name Produced item Wafer size
Production capacity, etc. Plan Intel Global Foundries Micron Technology Samsung Electronics TSMC
Fujian Electronics & Information; JHICC*Technology licensed by UMC
Nexchip (Powerchip)
Huali; HLMC
Innotron Memory
Yangtze Memory Technologies; YMTC *Tsinghua Unigroup acquired capital in XMC.
Yokkaichi Dalian Chengdu Hiroshima Xian Nanjing Quanzhou Hefei Shanghai Hefei Wuhan Y6 Fab 2 Fab 11 Fab 15
17 Line (II)
Fab 2 3D-NAND Foundry DRAM Niche DRAM Foundry Foundry LCD driver IC DRAM 3D-NAND 3D-NAND 12 inches 12 inches 12 inches 12 inches 12 inches 12 inches 12 inches 12 inches 12 inches 12 inches 100,000 wafers/month 80,000 wafers/month 20,000 wafers/month 160,000 wafers/month 200,000 wafers/month 60,000 wafers/month 80,000 wafers/month 40,000 wafers/month 40,000 wafers/month 125,000 wafers/month 50,000 wafers/month
Production lines will be installed by FY 2017
To be completed in summer of FY 2018
Under construction Equipment will be installed in February 2018
A new factory building is under construction for mass production of 1Xnm DRAMs
Capacity will be increased from 130,000 wafers/month to 200,000 wafers/month in 2019
Production will start in the second half of 2018
The factory building is expected to be completed in October 2017 To go online in 1Q 2018
Equipment to produce 3,000 wafers/month was installed in April-June 2017
Capacity will be increased by 10,000 wafers/month in 1Q 2018. Equipment will be installed in 2Q 2018
Equipment will be installed in November 2017
Equipment will be installed in 2Q 2018
Aiming to increase capacity to 1 million wafers/month by 2030
N-Y2 3D-NAND
3D-NAND 12 inches
12 inches
<Maintenance and strengthening of quality edge>
◆
SA Grade HF quality
◆
Product technology generation
≥45 nm
28 nm
≤16 nm
Our product grade
SA/SA-X
SA-XX
SA-XXX
Metal impurities level
<100 ppt
< 10 ppt
<1 ppt
Management size
of particle
0.2/0.1 um
0.05 um
0.03 um
Succeeded in ultra-high-purity
Further strengthening particle management
High resolution ICP-MS
Liquid-borne particle counter
©Thermo Fisher Scientific K. K. ©RION CO., LTD.
We respond the needs of semiconductor manufacturers
<Change in shipping volume of high-purity hydrofluoric acid (semiconductors and LCDs)>
2Q 34,199
2Q
33,669 32,698 2Q 2Q
31,257 (2Q) 39,665 (Full-year) 69,132 (Full-year) 65,177 (Full-year) 65,241 (Full-year) 66,069 3Q 62,075
0
10,000
20,000
30,000
40,000
50,000
60,000
70,000
80,000
FYE 3/2014
FYE 3/2015
FYE 3/2016
FYE 3/2017
FYE 3/2018
Batteries
Features of our products
Changes in lithium-ion battery market size and trends
in electric-powered vehicles
Launch of electrolyte business for lithium-ion
secondary batteries in China
(1) Used as main material comprising lithium-ion secondary batteries and commercialized much ahead of other companies
(
2) Because of the product’s high purity, it is
recently being used for high-performance lithium-ion secondary batteries.
Product name
(related to batteries)
Description
Lithium
hexafluorophosphate
Electrolyte for lithium-ion secondary batteries Electrolyte for other batteries
Lithium tetra fluoroborate Electrolyte and additives for lithium-ion primary and secondary batteries
Additive for batteries Additive for lithium-ion batteries
<Lithium hexafluorophosphate particle form> <Lithium tetra fluoroborate> <Large-size container: 1 m3>
<Changes in lithium-ion battery market size and trends in electric-powered vehicles>
0
5000
10000
15000
20000
25000
30000
2013 2014 2015 2016 2017 2018 2019 2020
世
界
の
L
IB
販
売
金
額
[
億
円
]
実
績
ら
び
予
測
年
車載用
LIB
民生用
LIB
Growth of in-car LIB is expected.
(Results) (Prospects and forecast)
Source: Materials of Fuji Chimera Research Institute, Inc.
<Launch of electrolyte business for lithium-ion secondary batteries in China>
Outline
Name
Quzhou BDX New Chemical Materials Co., Ltd. (established in December 2015)Location
17 Nianhua Road, Kecheng District, Quzhou City, Zhejiang Province, People's Republic of ChinaBusiness
lineup
Lithium hexafluorophosphate (LiPF6)
Research & development and production of byproduct hydrofluoric acid for industrial use, hydrochloric acid and other fluorine-containing chemical system products
Sales of in-house products and provision of related services
Capital fund
70 million Chinese yuan (1,330 million yen*) Stella: 25.0%; Quzhou NGF Chemicals Co., Ltd.: 75.0%Objectives
In China, continuous growth of lithium-ion secondary battery industry is anticipated. A local production system is established to handle the demand in China.Details of
cooperation
Part of the manufacturing facilities of electrolyte for lithium-ion batteries is relocated to a joint company. The joint company produces the electrolyte for lithium-ion batteries by the relocated facilities and markets the electrolyte in and outside China.
■
June 2017
Start of operation of manufacturing
facilities.
(Manufacturing capacity: 1,300 t/year at
maximum)
On completion of product evaluation
(including suppliers), sales are slated to
be started.
<Plan and schedule>
<Launch of electrolyte business for lithium-ion secondary batteries in China>
■
Quzhou BDX New Chemical Materials Co., Ltd.
Product and material warehouse
Manufacturing building
FYE 3/2013 FYE 3/2014 FYE 3/2015 FYE 3/2016 FYE 3/2017 FYE 3/2018 FYE 3/2019 FYE 3/2020
Fiscal Year
Results
Prospects
<Additive for lithium-ion batteries>
Roles that additive play
◆ High-temperature
endurance
◆ High conductivity (low
temperature)
◆ Increased capacity ◆ Low resistance ◆ Flame retardance
<Schematic diagram of lithium-ion battery inside>
The solid electrolyte interface (SEI), wherein the electrode comes in contact with the electrolyte, is important.
Electrolytic solution
Discharge Charge
GMP-related
Standards for Manufacturing Control and Quality Control for Drugs and Quasi-drugs
Three principles:
“
Reducing human errors to the lowest level"
“
Preventing contamination and product quality
loss“
“
Designing systems to assure high product quality"
<GMP(Good Manufacturing Practice)>
Fo
r
ma
nu
fac
turin
g
se
mic
on
du
ctors
Ex
pand
ed
to
pr
oduc
ts
re
lated
to
daily c
ommodities
<Examples of products for drugs>
Sodium fluoride
Sodium monofluorophosphate
Tin fluoride
<Actions of fluorine on teeth>
■
To suppress Streptococcus mutans from
producing acid
(Cavity prevention)
■
To promote tooth remineralization
■
To form tooth resistance to acid
(To form fluoroapatite)
Sales
started.
4. Medical Business
Corporate Profile (as of December 31, 2017)
Boron Neutron Capture Therapy (BNCT)
Establishment of enrichment technology/Features of enriched
Boron/Applications of 10B compounds
World’s First Accelerator
-based BNCT Clinical Trial
Boron-based Drug SPM-011 for BNCT Designated for MHLW
Prioritized Review System for innovative medicines
“SAKIGAKE”
Corporate name:
STELLA PHARMA CORPORATION
Head Office:
3-2-7 Koraibashi, Chuo-ku, Osaka-shi, Osaka
Representatives:
Tomoyuki Asano, Representative Director and President
Established:
June 2007
Business lineup
Research and development, manufacture and marketing, etc. of drugs and
medical devices
Capital:
1,900 million yen
Shareholders:
Stella Chemifa Corporation
Innovation Network Corporation of Japan
Sumitomo Heavy Industries, Ltd.
Laboratory:
Sakai Drug Discovery Research Center
(Naka-ku, Sakai-shi, Osaka)
URL
http://www.stella-pharma.co.jp/
Boron Neutron Capture Therapy (BNCT) is a particle beam radiation therapy which
damages cancer cells specifically by making the best of
nuclear fission reactions
between
boron 10
, stable isotope of boron, and
thermal neutrons
using small energy.
Administration of boron (Boron-10)
compound
Boron (Boron-10) compound is
selectively brought into cancer cells.
Irradiating with thermal neutron ray
causes boron (Boron-10) to fission.
Cancer cell which brought in boron
(Boron-10) compound is selectively destroyed.
Prompt gamma ray 478 keV
7Li Recoil nucleus
0.84 MeV
4He nucleus (α particle)
1.47 MeV
4 μm
9 μm
10
B
Thermal neutron
We established a mass production technology of
10B for the first time in Japan and in November
2000, the only enrichment plant in Japan was completed.
■
Establishment of enrichment technology
Generation
10
B
10B
10
B
10B
10
B
10B
10
B
10
B
10B
10
B
10B
10
B
Enrichment andseparation
<The
only
10B enrichment plant in Japan> (completed in November 2000)
■
Features of enriched Boron
10
B offers properties of remarkably high neutron absorption capacity, and by increasing
10B concentration, the
absorption capacity is improved significantly.
■
Applications of
10
B compounds
•
Neutron-absorbing material of spent nuclear fuel transportation-and-storage containers
•
Material of control rods of nuclear reactors and rack material of spent nuclear fuel pools
•
Excess reaction control of pressurized-water reactors by immersing them in primary cooling water
The world’s first BNCT clinical trials using the boron
-based drug for BNCT (SPM-011) , which Stella
Pharma developed as well as accelerator-based irradiation system for BNCT, developed by Sumitomo
Heavy Industries, “Phase II study for recurrent malignant glioma (high
-
grade brain tumor)” started in
December 2015 and “Phase II study for head and neck cancer”
in June 2016. These trials were started
after submitting the clinical trial plan notification, and are still ongoing.
Pharmaceutical solution bag made by
Stella Pharma
Accelerator-based irradiation system made by Sumitomo Heavy Industries
World’s first BNCT clinical trial
Recurrent malignant glioma (high-
grade brain tumor)”
December 2015, Phase II study started.
Head and neck cancer
June 2016, Phase II study started.
Assumed flow chart, from clinical trial to approval application
Phase I study
Phase II study
Approval application (scheduled)Neutron dose is increased stepwise to check safety. Verification of effect by the dose decided.
Boron-
based drug “SPM
-
011” for BNCT for which Stella Pharma Corporation performs clinical
development was designated by Ministry of Health, Labour, and Welfare (MHLW) for “Prioritized
Review System for innovative medicines ‘SAKIGAKE’” On April 21,
2017.
<Boron-based Drug SPM-011 for BNCT Designated for MHLW Prioritized Review
System for innovative medicines “SAKIGAKE”>
Drug name
Intended indications and effects
Name or trade name of
applicant
SPM-011
•
Recurrent malignant gliomas
•
Unresectable locally recurrent head
and neck cancer and locally-advanced
head and neck cancer
(non-squamous cell carcinoma)
Stella Pharma Corporation
The BNCT system (accelerator-based irradiation system) of Sumitomo Heavy Industries, Ltd., which
jointly carries out the clinical study was assigned for the target item of the said system as a medical
device on February 28, 2017, too.
“Prioritized Review System for innovative medicines ‘SAKIGAKE’”
Photo: Courtesy of Professor Ono at Kyoto University Research Reactor Institute
Signing the joint development agreement with Sumitomo Heavy Industries, Ltd., which has expertise
in the automated synthesis of PET drugs, enabled us to develop PET drugs and take a major step
forward to commercialization.
Joint research is ongoing with Osaka Prefecture University, Osaka University, the National Cancer
Center, and other well-established research organizations though a project adopted by the Japan
Agency for Medical Research and Development (AMED).
In order to provide total medical care from early cancer diagnosis to therapy, we
will continue to carry out research and development in coming years.
(Left) MRI image of brain tumors
(Right) [18F]FBPA PET image of brain tumors
We have undertaken the development of PET diagnostic technology using [
18F]FBPA, which attracts
researchers and industry attention as a new PET drug used for “PET diagnosis,”
which is a
technology useful for early detection of cancers.
To
be able to detect “brain tumor,” which is difficult to
detect at present.
Able to simply carry out PET diagnosis by [
18F]FBPA
for institutes where PET diagnosis is conducted at
present.
To be able to judge whether BNCT can be applied.
Features of PET diagnosis using [
18F]FBPA
5. Transportation Business
Corporate Profile
(as of December 31, 2017)
Transportation System by Cooperation with Domestic
Bases
Overseas Bases
Corporate name:
BLUE EXPRESS CORPORATION
Head Office:
10 Ohamanishi-machi, Sakai-ku, Sakai-shi
Representatives:
Kiyonori Saka, Representative Director and President
Established:
June 1991
Capital:
350 million yen
Business lineup
Common motor trucking / International intermodal transport /
Warehousing / Customs clearing agent / sales, rental and lease of
containers, tanks, etc. /
Automobile maintenance services / Business related to life insurance and
non-life insurance agent, etc.
URL
http://www.blue-express.co.jp/
Shipping terminals
Sendai Office
Kanto Office
Yokohama Office
Shimizu Office
Nagoya Office
Ohama Office
Kobe Office
Kitakyushu Office
Customs clearance sites
Tokyo Office
Yokohama Office
Osaka Office
Ohama Office
Kitakyushu Office
Blue Express (Shanghai) International Trade Inc.
Blue Express (Shanghai) International Freight Forwarding Co., Ltd.
China (Shanghai)
Stella Express (Singapore) Pte Ltd.
Singapore
Storage
Transportation
Customs
clearance
Container
service
<International Intermodal Logistics system>
●High-purity chemicals
●Poisonous and deleterious substances ●Hazardous material
<Future Activities>
■
To steadily expand business with priority given to the improvement of customer satisfaction
To further improve quality, etc. of international intermodal logistics service
■
To maintain continuous investment for further growth
To establish the additional hazardous substance warehouse
(construction to be started in April 2018)
■
To further strengthen business operation base and revenue base
6. Future Activities
Approaches to Advanced Energy Devices
New additive for advanced lithium-ion Batteries
Electrolyte for Post Lithium-ion Batteries
Development of Catalysts for Polymer Electrolyte
Fuel Cells (PEFCs)
Fluorinated Carbon Nanotubes
We are leveraging our expertise and experience in fluorine chemistry with an aim to make
original products that would serve as our next-generation prime source of earnings.
Development of catalysts
for fuel cells
Fuel cell vehicle (FCV)
Residential fuel cell system
Fluorine
chemistry
(core technology)
LIB
additives
know-how
Surface
treatment
technology
Mass
production
technology for
high-purity
electrolytes
Development of electrolyte for post
lithium-ion batteries
Launch of sodium ion battery prototypes (Image is for illustrative purposes only)
New additive for
advanced lithium-ion
batteries
Roll-out to automotive applications
Roll-out to residential applications
Conducted trials for a wide range of applications from
in-car to stationary LIBs across the globe
We were highly rated for our advanced high
capacity battery mechanism
Development Phase
Future Developments
Combine with user battery materials
Appearance of the new additive
New Additive Concept
Improved characteristics by film forming
Effect of improved characteristics by
new additive
Improved characteristics
Longer battery life Slower degradation under high
temperatures
Lower resistance under low temperatures
Work on developing mass production technique
<New Additive for Advanced Lithium-ion Batteries>
Separator Electrolytic solution
Discharge Charge
Positive-electrode material Negative-electrode material With additive No additive D ischa rg e cap aci ty retent ion r atio [ %]
Na-ion battery-equipped electric bicycle
(Image is for illustrative purposes only)Users rated our world-quality samples very high
Future Developments
Work on developing mass production technique
Developed a production process for high-purity NaPF6
to be used in future mass production
High-purity electrolyte for sodium-ion batteries
(NaPF6)
Na Li
1. Abundant resources (400 times more than Li) 2. Similar battery production process as LIB
Importance of sodium-ion batteries
Comparison of resource amounts
<Electrolyte for Post Lithium-ion Batteries>
Development Phase
Cla rke nu m be rs (rel a tiv e a bu nd a nc e of e le m e nts in Ea rth's c rus t)Verified that the original surface treatment improved
performance in a low humidity environment
Development Phase
Future Developments
To promote and begin trials for users
Appearance of developed fuel cell
catalyst
Hydrogen gas
Fuel electrode
Air (oxygen gas)
H
+Air electrode
Motor rotation
e
- (Electron)Out
put
pot
ent
ial
[V]
Out
put
[
W
/c
m
2]
Move on to non-platinum catalyst research
Conventional catalysts do not perform well in a low humidity environment.
Current density [mA/cm2]
The newly developed catalyst performs better in a
<Development of Catalysts for Polymer Electrolyte Fuel Cells (PEFCs)>
Developed Catalyst
F
F
F
F
F
F
F
Fluorinated carbon nanotube dispersed liquid
Non-fluorinat ed CNT Fluorinated CNT
F-CNT dispersed liquid with high
dispersibility without using any
surfactant.
Applications in displays
Conductive film made with fluorinated CNT
Non-fluorinated
Coated with fluorinated CNT
Applications in exterior coatings
25% stronger
Epoxy resin Fluorinated CNT
epoxy composite Fluorination of carbon nanotube
Transparent conducting film and antistatic film
Composite material (compounding of CNT
and resin)
Antistatic film prototype sample
Applications in engineering plastics
Development of low refractive index fluoride material for antireflection film
<Fluoride Nanoparticles>
Evolution and market expansion of smart cars, IoT, and wearable devices
Increased demand of coating material that increases display panel visibility
Hollow introduced in particles
by particle morphology control
50nm
Conventional product n=1.38 Developed product n=1.32
50nm
http://style.nikkei.com/article/DGXMZO11794240X10C17A1000000